Which substances can lead to a determination of intoxication?

The determination of intoxication is influenced by a broad range of substances that affect an individual's cognitive and physical abilities. When considering the correct answer, it's important to recognize that intoxication can arise from any substance that impairs judgment, coordination, or reaction times. This includes legal substances like alcohol, prescription medications, and even over-the-counter drugs, as well as illegal drugs and volatile substances such as glue vapor. Each of these can alter a person's mental state and capacity to operate a vehicle or perform other tasks safely.

This comprehensive view reflects the reality of substance use and its impact on behavior, confirming that not just specific categories or types of substances are relevant; rather, any substance capable of affecting mental or physical functioning can lead to a determination of intoxication. Thus, the correct response encompasses a wide range of potentially impairing substances.